San Francisco is a wonderful place to get married -- the weather was absolutely beautiful for us (this was our biggest worry, and good weather in SF can never be guaranteed). The area can be very expensive in regard to hotels and attractions, so let your guests know early about the events that you have planned!
We LOVED our ceremony and reception venue -- the Presidio Log Cabin. It was a great mix of rustic and casual beauty, and the surrounding historic areas were great for pictures. Additionally, it was within walking distance to the Golden Gate Bridge, another fantastic photo op!
The La Luna was a great affordable inn -- clean rooms and decent service. It was a great low-cost option for some of our more budget-conscious friends... very near to the reception site, close to Marina bars and restaurants, and still in a decent neighborhood. The only problem was that some of our crowd were a little loud, and were assessed the $150 noise complaint fee! If you stay at the La Luna, be sure to keep it quiet -- they are strict with enforcement of that rule!
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