You have a big Irish family, I'm sure they are boisterous and friendly and not likely to let any guest go un-welcomed at your wedding. Your friends will find someone to party with if they don't get to bring a guest... There is really no reason to do "And Guest", just do a good seating plan so they have folks at their table they have something in common with.
If your intended guest has a significant other, you should be aware of that (If you are not aware, the other is not that significant.) Invite the significant other by naming them on the invitation. Do Not send the significant other a separate invitiation unless you want them to attend the wedding in the event the couple breaks up! Eek!
It's your wedding, so do what reduces your stress. At my wedding, the "no-shows" (i.e. didn't cancel so we had to pay for the dinner they didn't eat) were the "significant others" who I suspect really just didn't want to be at a wedding with a bunch of people they didn't know.
Good luck!!!
Written on Mar. 01, 2010